Abstract: Copper (II) chloride is an inorganic compound used as a source of copper ions for the treatment of several diseases like cancer, inflammation, hematological and neurological disorders. This article was aimed to evaluate the effect of The Trivedi Effect® – Energy of Consciousness Healing Treatment on the physicochemical and thermal properties of copper (II) chloride using PXRD, DSC, and TGA/DTG analysis. Copper chloride was divided into two parts, one part of copper chloride was considered as control (no Biofield Treatment was provided), while second part received The Trivedi Effect® – Biofield Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Alice Branton. The PXRD analysis showed that the relative intensities of the characteristic diffraction peak in Alice’s treated sample were significantly changed from -77.37% to 205.56% compared with the control sample. The crystallite size of the characteristic diffraction peak in the treated sample was altered from -14.29% to 40.01% compared with the control sample. The DSC analysis showed that the melting point of the treated copper chloride was significantly increased by 2.91% with a reduced latent heat of fusion (∆H) by 28.73% compared to the control sample. The melting temperature of the 2nd peak in the treated sample was significantly increased by 7.08% with a significant enhancement of ∆H by 77.37% compared with the control sample. The decomposition temperature of the treated sample was increased by 2.36% with a significant reduction of the enthalpy of decomposition by 18.46% compared with the control sample. The TGA analysis revealed the three steps of thermal degradation. The percentage weight loss in the treated sample was decreased by 0.47% and 9.63% in the 1st and 2nd steps of degradation, respectively, while the weight loss in the 3rd step was increased by 2.45% compared with the control sample. The total weight loss in the treated sample was increased by 1.32% compared with the control sample. The DTG analysis showed that the maximum thermal degradation temperature (Tmax) in the 1st, 2nd, and 3rd peaks of the Biofield Treated sample were increased by 1.20%, 2.00%, and 4.61% compared with the control sample. Briefly, The Trivedi Effect® – Energy of Consciousness Healing Treatment might produce a polymorphic form of copper (II) chloride that could be more stable during manufacturing, delivery or storage conditions than the untreated sample. The Biofield Energy Treated copper chloride would provide better therapeutic response against cancer, inflammation, wound healing, etc.

Abstract: There are numerous scientific studies on vitamin D3 reported to have many important roles viz. in bone metabolism, osteoporosis, immunity, and useful in several diseases, e.g., cancers, cardio-vascular, and neurodegenerative diseases. Surprisingly, there is little information available about the concentration of 25-hydroxyvitamin D3 in the blood, which is the best indicator of vitamin D3 status after its oral absorption. However, the biological activity of vit-D3 is mediated via the formation of the active metabolite, 1-α, 25-dihydroxyvitamin D3. There are several factors which affect its absorption and first-pass metabolism that lead to have very low plasma concentrations of both the metabolites (25-hydroxyvitamin D3 and 1-α, 25-dihydroxyvitamin D3) following an oral administration. Therefore, the present study was performed to determine the effects of The Trivedi Effect®-Energy of Consciousness Healing Treatment on vit-D3 and rats through the measurement of plasma 25-hydroxyvitamin D3 concentrations after the oral administration of vit-D3 in rats. The test item, vit-D3 was divided into two parts. One part was denoted as the control (without Biofield Energy Healing Treatment), while the other part was defined as the Biofield Energy Treated sample, which received the Biofield Energy Healing Treatment by renowned Biofield Energy Healer, Alice Branton. Additionally, one group of animals also received Consciousness Energy Healing Treatment per se by the Healer under similar conditions. Vitamin D3 oral formulations were administrated by oral gavage at a dose of 500 µg per kg in groups viz. G1 (untreated Vitamin D3), G2 (Biofield Treated Vitamin D3) and G3 (Biofield Treated animals received untreated Vitamin D3) group. The Biofield Energy Healing Treatment significantly altered the relative oral exposure (AUC0–t) of 25-hydroxyvitamin D3 by 54.62% in G2 group compared to the control group, G1. The Biofield Energy Treatment also altered plasma peak concentration (Cmax) of 25-hydroxyvitamin D3 by 53.8% and 7.6% in G2 and G3 groups, respectively compared to the control group. After oral administration, plasma concentrations of 25-hydroxyvitamin D3 in control group (G1) declined with slow excretion rate and the elimination half-life (T1/2) was 100.59 hours. The oral elimination half-life (T1/2) of 25-hydroxyvitamin D3 in G2 and G3 were 69.09 hours and 55.76 hours, respectively. The mean residence time (MRTlast) and elimination rate constant (Kel) remained unaltered in all three groups. The Trivedi Effect®-Energy of Consciousness Healing Treatment could be an innovative strategy which opens new avenues to overcome poorly absorbed pharmaceuticals/nutraceuticals/herbal extracts and can improve the therapeutic performance of orally active molecules.