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Zaba, M.; Kirmeier, T.; Ionescu, I.A.; Wollweber, B.; Buell, D.R.; Gall-Kleebach, D.J.; Schubert, C.F.; Novak, B.; Huber, C.; Kohler, K.; Holsboer, F.; Putz, B.; Muller-Myhsok, B.; Hohne, N.; Uhr, M.; Ising, M.; Herrmann, L.; Schmidt, U. |

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Title |
Identification and characterization of HPA-axis reactivity endophenotypes in a cohort of female PTSD patients |
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Journal Article |
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Year |
2015 |
Publication |
Psychoneuroendocrinology |
Abbreviated Journal |
Psychoneuroendocrinology |
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55 |
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102-115 |
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Fkbp5; Gene expression; Ptsd; PTSD subtypes; Posttraumatic stress disorder; Stress reactivity; Trier Social Stress Test |
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Analysis of the function of the hypothalamic-pituitary-adrenal (HPA)-axis in patients suffering from posttraumatic stress disorder (PTSD) has hitherto produced inconsistent findings, inter alia in the Trier Social Stress Test (TSST). To address these inconsistencies, we compared a sample of 23 female PTSD patients with either early life trauma (ELT) or adult trauma (AT) or combined ELT and AT to 18 age-matched non-traumatized female healthy controls in the TSST which was preceded by intensive baseline assessments. During the TSST, we determined a variety of clinical, psychological, endocrine and cardiovascular parameters as well as expression levels of four HPA-axis related genes. Using a previously reported definition of HPA-axis responsive versus non-responsive phenotypes, we identified for the first time two clinically and biologically distinct HPA-axis reactivity subgroups of PTSD. One subgroup (“non-responders”) showed a blunted HPA-axis response and distinct clinical and biological characteristics such as a higher prevalence of trauma-related dissociative symptoms and of combined AT and ELT as well as alterations in the expression kinetics of the genes encoding for the mineralocorticoid receptor (MR) and for FK506 binding protein 51 (FKBP51). Interestingly, this non-responder subgroup largely drove the relatively diminished HPA axis response of the total cohort of PTSD patients. These findings are limited by the facts that the majority of patients was medicated, by the lack of traumatized controls and by the relatively small sample size. The here for the first time identified and characterized HPA-axis reactivity endophenotypes offer an explanation for the inconsistent reports on HPA-axis function in PTSD and, moreover, suggest that most likely other factors than HPA-axis reactivity play a decisive role in determination of PTSD core symptom severity. |
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Max Planck Institute of Psychiatry, Clinical Department, Kraepelinstrasse 10, 80804 Munchen, Germany. Electronic address: uschmidt@mpipsykl.mpg.de |
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0306-4530 |
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PMID:25745955 |
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UU @ jana.mullerova @ |
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42193 |
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Steenweg, R.J.; Hennin, H.L.; Bêty, J.; Gilchrist, H.G.; Williams, T.D.; Crossin, G.T.; Love, O.P. |

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Title |
Sources of diel variation in energetic physiology in an Arctic-breeding, diving seaduck |
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Journal Article |
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2015 |
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General and Comparative Endocrinology |
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216 |
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39-45 |
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Arctic; Corticosterone; Diel rhythm; Energetic physiology; Sea duck; Triglyceride |
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Diel variation in baseline glucocorticoid (GC) secretion influences energetics and foraging behaviors. In temperate breeding, diurnal vertebrates, studies have shown that daily patterns of baseline GC secretion are influenced by environmental photoperiod, with baseline GCs peaking prior to sunrise to stimulate waking and foraging behaviors. Measures of physiological energy acquisition are also expected to peak in response to foraging activity, but their relationship to GC levels have not been well studied. In contrast to temperate breeding species, virtually nothing is known about diel GC and energetic metabolite secretion in Arctic breeding species, which experience almost constant photoperiods in spring and summer. Using a ten-year dataset, we examined the daily, 24-h pattern of baseline corticosterone (CORT) and triglyceride (TRIG) secretion in approximately 800 female pre-breeding Arctic-nesting common eiders (. Somateria mollissima). We related these traits to environmental photoperiod and to tidal cycle. In contrast to temperate breeding species, we found that that neither time of day nor tidal trend predicted diel variation in CORT or TRIG secretion in Arctic-breeding eiders. Given the narrow window of opportunity for breeding in polar regions, we suggest that eiders must decouple their daily foraging activity from light and tidal cycles if they are to accrue sufficient energy for successful breeding. As CORT is known to influence foraging behavior, the absence of a distinct diel pattern of CORT secretion may therefore be an adaptation to optimize reproductive investment and likelihood for success in some polar-breeding species. © 2015 Elsevier Inc. |
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Simon Fraser University, Burnaby, BC, Canada |
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Export Date: 17 March 2016 |
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McgGll @ elizabethburgess @ |
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42530 |
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Calignano, F.; Tommasi, T.; Manfredi, D.; Chiolerio, A. |

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Title |
Additive Manufacturing of a Microbial Fuel Cell – A detailed study |
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2015 |
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Scientific Reports |
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5 |
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Cited By :1; Export Date: 2 November 2016 |
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IIT-CSF @ alessandro.chiolerio @ |
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42774 |
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Jagdale, P.; Chiolerio, A.; Naderi, A.; Roppolo, I.; Rattalino, I.; Tagliaferro, A. |

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Title |
MWCNT polymer nano composites for piezoresistivity and percolation—principles and applications |
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Book Chapter |
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2015 |
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Carbon for Sensing Devices |
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209-226 |
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Export Date: 2 November 2016 |
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IIT-CSF @ alessandro.chiolerio @ |
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42782 |
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Scalisi, R.G.; Paleari, M.; Favetto, A.; Stoppa, M.; Ariano, P.; Pandolfi, P.; Chiolerio, A. |

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Inkjet printed flexible electrodes for surface electromyography |
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Journal Article |
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2015 |
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Organic Electronics: physics, materials, applications |
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18 |
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89-94 |
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Cited By :3; Export Date: 2 November 2016 |
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IIT-CSF @ alessandro.chiolerio @ |
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42784 |
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Varma, V.; Ratnam, J.; Viswanathan, V.; Osuri, A.M.; Biesmeijer, J.C.; Madhusudan, M.D.; Sankaran, M.; Krishnadas, M.; Barua, D.; Budruk, M.; Isvaran, K.; Jayapal, R.; Joshi, J.; Karanth, K.K.; Krishnaswamy, J.; Kumar, R.; Mukherjee, S.; Nagendra, H.; Niphadkar, M.; Owen, N.; Page, N.; Prasad, S.; Quader, S.; Nandini, R.; Robin, V.V.; Sait, S.M.; Shah, M.A.; Somanathan, H.; Srinivasan, U.; Sundaram, B. |

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Title |
Perceptions of priority issues in the conservation of biodiversity and ecosystems in India |
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Journal Article |
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2015 |
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Biological Conservation |
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187 |
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201-211 |
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biodiversity; Conservation; Ecosystems; India; Perceptions |
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0006-3207 |
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CES @ dilipnaidu.gt @ |
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42955 |
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Chitra-Tarak, R.; Ruiz, L.; Pulla, S.; Dattaraja, H.S.; Suresh, H.S.; Sukumar, R. |

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And yet it shrinks: A novel method for correcting bias in forest tree growth estimates caused by water-induced fluctuations |
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Journal Article |
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2015 |
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Forest Ecology and Management |
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336 |
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129-136 |
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Above-ground biomass; Carbon; Permanent sampling plot; Reversible stem flexing; Seasonally dry tropical forest; Tree shrinkage |
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0378-1127 |
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CES @ dilipnaidu.gt @ |
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42959 |
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Author |
Borges, R.M. |

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Title |
How to be a fig wasp parasite on the fig–fig wasp mutualism |
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Journal Article |
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2015 |
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Current Opinion in Insect Science |
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8 |
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34-40 |
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The nursery pollination mutualism between figs and pollinating fig wasps is based on adaptations that allow wasps to enter the enclosed inflorescences of figs, to facilitate seed set, and to have offspring that develop within the nursery and that leave to enter other inflorescences for pollination. This closed mutualistic system is not immune to parasitic fig wasps. Although the life histories and basic biology of the mutualists have been investigated, the biology of the fig wasp parasites has been severely neglected. This review brings together current knowledge of the many different ways in which parasites can enter the system, and also points to the serious lacunae in our understanding of the intricate interactions between gallers, kleptoparasites, seed eaters and parasitoids within this mutualism. |
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2214-5745 |
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CES @ dilipnaidu.gt @ |
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42971 |
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Author |
Ramachandra, T.V.; Bharath, A.H.; Sowmyashree, M.V. |

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Title |
Monitoring urbanization and its implications in a mega city from space: Spatiotemporal patterns and its indicators |
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Journal Article |
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2015 |
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Journal of Environmental Management |
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148 |
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67-81 |
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Delhi; Remote sensing; Spatial metrics; Urbanization; Urban sprawl |
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0301-4797 |
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CES @ dilipnaidu.gt @ |
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43048 |
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Author |
Agarwal, I.; Karanth, K.P. |

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A phylogeny of the only ground-dwelling radiation of Cyrtodactylus (Squamata, Gekkonidae): diversification of Geckoella across peninsular India and Sri Lanka |
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Journal Article |
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2015 |
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Molecular Phylogenetics and Evolution |
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82, Part A |
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193-199 |
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Aridification; cryptic species; historical biogeography; Mid-Miocene climatic optimum |
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1055-7903 |
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CES @ dilipnaidu.gt @ |
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43068 |
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